Role of chelates in treatment of cancer.
نویسندگان
چکیده
Chelates are used in cancer as cytotoxic agent, as radioactive agent in imaging studies and in radioimmunotherapy. Various chelates based on ruthenium, copper, zinc organocobalt, gold, platinum, palladium, cobalt, nickel and iron are reported as cytotoxic agent. Monoclonal antibodies labeled with radioactive metals such as yttrium-90, indium-111 and iodine-131 are used in radioimmunotherapy. This review is an attempt to compile the use of chelates as cytotoxic drugs and in radioimmunotherapy.
منابع مشابه
کارایی روی- آمینوکلات‌های سنتز شده در تأمین روی مورد نیاز گندم
This pot experiment was carried out to investigate the efficacy of certain Zn-amino chelates, i.e. Zn-glycine [Zn(Gly)2], Zn-arginine [Zn(Arg)2] and Zn-histidine [Zn(His)2] in supplying zinc for wheat was compared with a commercial Zn-sulfate fertilizer. Three wheat cultivars, differing in Zn-efficiency, including Back Cross Rowshan, Kavir and Durum were planted at Research Greenhouse of Isfaha...
متن کاملRole of Photodynamic Therapy in the Treatment of Oral Cancer: A Review
Oral cancer is a major public health problem worldwide and is among the ten most common cancers. Despite the advances in research and treatment, oral cancer is still one of the major challenges in medical science. Common treatments for this cancer include surgery, radiotherapy, and chemotherapy, as well as adjuvant photodynamic therapy (PDT). The aim of this study was to evaluate oral cancer an...
متن کاملThe Role of Epigenetics in Cancer Drug Resistance
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...
متن کاملRole of Adenosine receptor in lung cancer
Summary: Adenosine through adenosine receptor have a crucial role in biology of lung cancer. Recent study indicated adenosine receptors have a crucial role in various aspect of lung cancer from cell growth and metastasis to modulation of apoptosis and it could be considered as a potential candidate for treatment of the lung cancer.
متن کاملSynthesis and Characterization of Iron Oxide Nanoparticles by Thermal Decomposition Method of Iron (III) Chelates
Magnetic iron oxide nanoparticles have numerous applications in the biomedical field. This paper reports the preparation and properties of iron oxide nanoparticles synthesised by thermal decomposition method from iron chelates. The iron oxide nanoparticles were characterized by FTIR, powder XRD, VSM, SEM and TEM techniques. FTIR and powder XRD studies show that iron oxide was fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Indian journal of cancer
دوره 44 2 شماره
صفحات -
تاریخ انتشار 2007